Voxel-based morphometry of adulthood patients with temporal lobe epilepsy

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Voxel-based morphometry of adulthood patients with temporal lobe epilepsy

Background Partial epilepsy represents almost 70% of the epileptic syndrome. It is characterized by partial seizures that arise from the restricted area of the cerebral cortex. Temporal lobe epilepsy (TLE) is the most frequent form of cryptogenic partial epilepsies [1]. The mesial temporal sclerosis is the pathologic abnormality most frequently detected in post mortem studies of subjects with T...

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Neuroanatomical correlates of psychosis in temporal lobe epilepsy: voxel-based morphometry study.

BACKGROUND Temporal lobe epilepsy is associated with a significant risk of psychosis but there are only limited studies investigating the underlying neurobiology. AIMS To characterise neuroanatomical changes in temporal lobe epilepsy and comorbid psychosis. METHOD The study population comprised all individuals with temporal lobe epilepsy on the epilepsy database at the National Centre for E...

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Voxel-based morphometry reveals gray matter network atrophy in refractory medial temporal lobe epilepsy.

BACKGROUND Conventional volumetric studies have shown that brain structures functionally and anatomically related to the hippocampus are smaller in patients with drug-refractory medial temporal lobe epilepsy (MTLE). OBJECTIVES To determine the extent of gray matter atrophy in the brains of patients with MTLE and to examine the pattern of atrophy. DESIGN We performed a voxel-based morphometr...

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Comparison of temporal lobe epilepsy with hippocampal sclerosis and temporal lobe epilepsies due to other etiologies

  Background: This study compares the clinical characteristics of patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS) with those who have temporal lobe epilepsy (TLE) due to other etiologies.   Methods : In this retrospective study all patients with a clinical diagnosis of TLE were recruited in a referral outpatient epilepsy clinic at Shiraz University of Medical Sc...

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Single subject voxel-based analysis in mesial temporal lobe epilepsy

Introduction: Voxel-based morphometry is a widely used clinical tool for detection of voxel-wise structural shape changes in subject groups using MRI. A related technique, voxel-based relaxometry (VBR), may be used to map changes in T2. Traditionally the techniques have been used to compare groups of subjects. In this context, the voxel-based techniques may not be used for the categorisation of...

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ژورنال

عنوان ژورنال: BMC Geriatrics

سال: 2010

ISSN: 1471-2318

DOI: 10.1186/1471-2318-10-s1-a95